Mitochondria & Energy Metabolism

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Research interests

Mitochondrial plasticity
Mitochondrial gene expression
Nucleotide metabolism

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News

New paper at Cell Reports
July 2025
Our updated inventory of genes required for OXPHOS & findings on mito defects in Menieres is now out at Cell Reports! 🧫 New galactose #CRISPR screen 🎯 481 genes required for #OXPHOS ⚙️ #FAM136A in IMS proteostasis 👂 Mito defects in #Menieres Congratulations to first author Marcell Harhai and to the team! Link: https://www.jourdainlab.org/wp-content/uploads/2025/07/Harhai_CellReports_2025.pdf
New pre-print on pyrimidine synthesis
March 2025
New pre-print from the lab!
Uridine-sensitized screening identifies genes and metabolic regulators of nucleotide synthesis.
https://www.biorxiv.org/content/10.1101/2025.01.29.635272v1 By Abigail Strefeler et al.